ADC-5 drug-linker
ADC-5 drug-linker (Compound linker-payload 5) is a drug-linker conjugate for ADC with potent anti-tumor activity. ADC-5 drug-linker can be used to synthesize NLRP3 agonist 3.
Product Specifications
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
NC1=NC2=CC(C3=CC=NN3)=CC=C2C(N[C@H]4CC[C@H](OC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCN(C(C=C5)=O)C5=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C4)=C1
Molecular Formula
C43H60N10O11
Molecular Weight
893.00
References & Citations
[1]Riehl PS, et al. Antibody-Drug Conjugates of NLRP3 Agonists: How Overcoming Lysosomal Accumulation Necessitated Noncanonical Linker Attachments. J Med Chem. 2025 May 8;68 (9) :9799-9810.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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