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4-Aminobutyl 4-methylbenzenesulfonate

4-Aminobutyl 4-methylbenzenesulfonate is a PROTAC linker. 4-Aminobutyl 4-methylbenzenesulfonate can be used to synthesize PROTACs, such as PROTAC BRD4 Degrader-32 (HY-176449) [1].

Product Specifications

CAS Number

[100401-28-3]

UNSPSC

12352211

Field of Research

Cancer

Smiles

NCCCCOS(C1=CC=C(C)C=C1)(=O)=O

Molecular Formula

C11H17NO3S

Molecular Weight

243.32

References & Citations

[1]Lovato K, et al. Reductive C (sp2) -C (sp3) Coupling Protocol to Enable Linker Exploration of Cereblon E3-Ligase BRD4 Proteolysis-Targeting Chimeras. J Med Chem. 2025 May 22;68 (10) :10061-10074.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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