4-Aminobutyl 4-methylbenzenesulfonate
4-Aminobutyl 4-methylbenzenesulfonate is a PROTAC linker. 4-Aminobutyl 4-methylbenzenesulfonate can be used to synthesize PROTACs, such as PROTAC BRD4 Degrader-32 (HY-176449) [1].
Product Specifications
CAS Number
[100401-28-3]
UNSPSC
12352211
Field of Research
Cancer
Smiles
NCCCCOS(C1=CC=C(C)C=C1)(=O)=O
Molecular Formula
C11H17NO3S
Molecular Weight
243.32
References & Citations
[1]Lovato K, et al. Reductive C (sp2) -C (sp3) Coupling Protocol to Enable Linker Exploration of Cereblon E3-Ligase BRD4 Proteolysis-Targeting Chimeras. J Med Chem. 2025 May 22;68 (10) :10061-10074.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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