(S) -CDK2 degrader 6
(S) -CDK2 degrader 6 (Compound 8) is the S-enantiomer of CDK2 degrader 6. (S) -CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC50 of 166.7 nM in 24 h. (S) -CDK2 degrader 6 can be used for breast cancer research[1].
Product Specifications
CAS Number
3083777-51-6
UNSPSC
12352005
Target
CDK; Molecular Glues
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Field of Research
Cancer
Purity
99.69
Smiles
FC(F)(C12CC(C2)(C3=NN=C(N[C@@H]4[C@H](N(C5=CC(F)=C([C@H]6C(NC(CC6)=O)=O)C(F)=C5)C4)C)O3)C1)F
Molecular Formula
C23H22F5N5O3
Molecular Weight
511.44
References & Citations
[1]RITZÉN A, et al. Compounds that mediate protein degradation and methods of use thereof. WO2025090727A1. 2025-05-01.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Tpit (TBX19) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2G1]](https://cdn.genprice.uk/products/937/6868c39f994c49e6dc3fac91/imageurl/ta800683am.webp)
TA800683AM 100 µL
Tpit (TBX19) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2G1]
Sign In for Pricing
View Details 
BNC402462-100 1x 100 µL
Ki-67 (Proliferating Cell Marker) (MKI67/2462), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
