(R) -CDK2 degrader 6
(R) -CDK2 degrader 6 (Compound 7) is the R-enantiomer of CDK2 degrader 6. (R) -CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC50 of 27.0 nM in 24 h. (R) -CDK2 degrader 6 can be used for breast cancer research[1].
Product Specifications
CAS Number
3083777-50-5
UNSPSC
12352005
Target
CDK; Molecular Glues
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Field of Research
Cancer
Purity
99.55
Smiles
FC(F)(C12CC(C2)(C3=NN=C(N[C@@H]4[C@H](N(C5=CC(F)=C([C@@H]6C(NC(CC6)=O)=O)C(F)=C5)C4)C)O3)C1)F
Molecular Formula
C23H22F5N5O3
Molecular Weight
511.44
References & Citations
[1]RITZÉN A, et al. Compounds that mediate protein degradation and methods of use thereof. WO2025090727A1. 2025-05-01.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2
Available Sizes
Frequently Asked Questions
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