CDK2 degrader 6
CDK2 degrader 6 (compound 6) is an orally active and potent CDK2 molecular glue degrader with a DC50 of 46.5 nM. CDK2 degrader 6 can be used in the study of breast cancer[1].
Product Specifications
CAS Number
[3036606-92-2]
UNSPSC
12352005
Target
CDK; Molecular Glues
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.81
Smiles
O=C(C(CC1)C2=C(F)C=C(N3C[C@H](NC4=NN=C(C56CC(C6)(C(F)(F)F)C5)O4)[C@H]3C)C=C2F)NC1=O
Molecular Formula
C23H22F5N5O3
Molecular Weight
511.44
References & Citations
[1]Andreas RITZÉN, et al. Compounds that mediate protein degradation and methods of use thereof. WO2025090727A1. 2025-05-01.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
139679 200 µL
CDC25B (M-phase Inducer Phosphatase 2, Dual Specificity Phosphatase Cdc25B, CDC25HU2)
Ask
View Details