E3 Ligase Ligand-linker Conjugate 190
E3 Ligase Ligand-linker Conjugate 190 is a E3 ligase ligand-linker conjugate, used for the synthesis of BP-198 (HY-176440) [1].
Product Specifications
UNSPSC
12352211
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
C[C@@H](C(N[C@@H](C1CCCCC1)C(N2CCC[C@H]2C3=NC(C(C4=CC(OCCCN=[N+]=[N-])=CC=C4)=O)=CS3)=O)=O)NC
Molecular Formula
C29H39N7O4S
Molecular Weight
581.73
References & Citations
[1]Pan B, et al. Targeted protein degraders of SARS-CoV-2 Mpro are more active than enzymatic inhibition alone with activity against nirmatrelvir resistant virus. Commun Med (Lond) . 2025 Apr 26;5 (1) :140.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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LSP1 (47kD Actin Binding Protein, 47kD Actin-Binding Protein, 52kD Phosphoprotein, F Actin Binding and Cytoskeleton Associated Protein, LeufActin (leukocyte F-Actin Binding Protein), LeufActin, Leukocyte F Actin Binding Protein, Leukocyte specific Protein 1, LSP 1, Lsp1, LSP1_HUMAN, Lymphocyte specific Antigen WP34, Lymphocyte specific Protein 1, Lymphocyte specific Protein pp52, Lymphocyte-specific Antigen WP34, Lymphocyte-specific Protein 1, OTTHUMP00000014138, OTTHUMP00000014139, OTTHUMP00000014140, OTTHUMP00000069612, OTTHUMP00000069614, OTTHUMP00000069615, OTTHUMP00000069616, pp52, Protein pp52, S37 Protein, WP 34, WP34, ) discontinued
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LSP1 (47kD Actin Binding Protein, 47kD Actin-Binding Protein, 52kD Phosphoprotein, F Actin Binding and Cytoskeleton Associated Protein, LeufActin (leukocyte F-Actin Binding Protein), LeufActin, Leukocyte F Actin Binding Protein, Leukocyte specific Protein 1, LSP 1, Lsp1, LSP1_HUMAN, Lymphocyte specific Antigen WP34, Lymphocyte specific Protein 1, Lymphocyte specific Protein pp52, Lymphocyte-specific Antigen WP34, Lymphocyte-specific Protein 1, OTTHUMP00000014138, OTTHUMP00000014139, OTTHUMP00000014140, OTTHUMP00000069612, OTTHUMP00000069614, OTTHUMP00000069615, OTTHUMP00000069616, pp52, Protein pp52, S37 Protein, WP 34, WP34, ) discontinued
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