GW-117
GW-117 is a 5-HT2C receptor antagonist and a melatonin (MT1/MT2) receptor agonist. GW-117 shows antidepressant-like and anxiolytic-like effects[1].
Product Specifications
CAS Number
2260629-83-0
UNSPSC
12352005
Target
5-HT Receptor; Isotope-Labeled Compounds; Melatonin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC(NCCC1=CC=CC2=C1C=C(OC([2H])([2H])[2H])C(Cl)=C2)=O
Molecular Formula
C15H13D3ClNO2
Molecular Weight
280.76
References & Citations
[1]Gao N, et al. GW117: A novel serotonin (5-HT2C) receptor antagonist and melatonin (MT1 /MT2) receptor agonist with potential antidepressant-like activity in rodents. CNS Neurosci Ther. 2021 Jun;27 (6) :702-713.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
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