NSC-323241
NSC-323241 is a potent STT3A-mediated mega protein complex assembly inhibitor. NSC-323241 disrupts he endoplasmic reticulum (ER) mega complex nucleated by STT3A during dengue virus (DENV) and Zika virus (ZIKV) infection. NSC-323241 targets the binding of STT3A subcomplex with viral nonstructural proteins (e.g., NS2B, NS3) and host translocon proteins, disrupting the formation of viral replication microenvironment. NSC-323241 is promising for research of flavivirus infection, such as dengue fever and Zika virus[1].
Product Specifications
CAS Number
[79514-43-5]
UNSPSC
12352211
Target
Flavivirus
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
C/C(C1=CC=CC=N1)=N\NC(N2CC3CCC(CC3)C2)=[Se]
Molecular Formula
C16H22N4Se
Molecular Weight
349.33
References & Citations
[1]Liu T, Hanners N W, Tao H, et al. STT3A-mediated mega protein complex assembly during dengue and Zika virus infection[J]. iScience, 2025, 28 (6) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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