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TLCD1-IN-1

TLCD1-IN-1 (compound MB-4A) is a covalent TLCD1 inhibitor. TLCD1-IN-1 stereoselectively engages and inhibits TLCD1 in HepG2 cells[1].

Product Specifications

UNSPSC

12352005

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=C(N1[C@H](COP2(SCCO2)=S)[C@@H](C3=CC=C(Cl)C=C3)C1)C4=CC=C(OCO5)C5=C4

Molecular Formula

C20H19ClNO5PS2

Molecular Weight

483.93

References & Citations

[1]Sharma HA, et al. Proteomic Ligandability Maps of Phosphorus (V) Stereoprobes Identify Covalent TLCD1 Inhibitors. bioRxiv [Preprint]. 2025 Jan 31:2025.01.31.635883.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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