Lenalidomide-amide-pimelic acid
Lenalidomide-amide-pimelic acid is an E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based CRBN ligand and Linker (HY-Y1139). Lenalidomide-amide-pimelic acid can be used for synthesis of PROTAC MNK1 degrader-1 (HY-176428).
Product Specifications
CAS Number
2353496-83-8
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(CCCCCC(O)=O)NC1=CC=CC2=C1CN(C2=O)C3C(NC(CC3)=O)=O
Molecular Formula
C20H23N3O6
Molecular Weight
401.41
References & Citations
[1]Yang Z, et al. Discovery of P11-2: A Potent First-in-Class MNK1-Targeting PROTAC Degrader for the Treatment of Cancer. J Med Chem. 2025 May 22; 68 (10) :10092-10110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940257-500 1x 500 µL
Cytokeratin, HMW (AE-3), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740266-500 1x 500 µL
Human IgG Immunoglobulin (IG266), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471274-100 1x 100 µL
Cytokeratin 10 (Suprabasal Epithelial Marker) (AE20), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB0026-500 1x 500 µL
ACTH (Adrenocorticotrophic Hormone) (AH26), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471860-500 1x 500 µL
MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details