Lenalidomide-amide-pimelic acid
Lenalidomide-amide-pimelic acid is an E3 ligase ligand-linker conjugate that incorporates the Lenalidomide (HY-A0003) based CRBN ligand and Linker (HY-Y1139) . Lenalidomide-amide-pimelic acid can be used for synthesis of PROTAC MNK1 degrader-1 (HY-176428) [1].
Product Specifications
CAS Number
[2353496-83-8]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(CCCCCC(O)=O)NC1=CC=CC2=C1CN(C2=O)C3C(NC(CC3)=O)=O
Molecular Formula
C20H23N3O6
Molecular Weight
401.41
References & Citations
[1]Yang Z, et al. Discovery of P11-2: A Potent First-in-Class MNK1-Targeting PROTAC Degrader for the Treatment of Cancer. J Med Chem. 2025 May 22; 68 (10) :10092-10110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
