MNK1 ligand 1
MNK1 ligand 1 (Compound 5) is a MNK1 ligand. MNK1 ligand 1 can be used for synthesis of PROTAC MNK1 degrader-1 (HY-176428) [1].
Product Specifications
CAS Number
[1578413-29-2]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; MNK
Related Pathways
MAPK/ERK Pathway; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(NC1=NC=C(C2=CC=CC=C2)S1)C3CCNCC3
Molecular Formula
C15H17N3OS
Molecular Weight
287.38
References & Citations
[1]Yang Z, et al. Discovery of P11-2: A Potent First-in-Class MNK1-Targeting PROTAC Degrader for the Treatment of Cancer. J Med Chem. 2025 May 22; 68 (10) :10092-10110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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