Subquinocin
Subquinocin is a CYLD inhibitor that inhibits USP family deubiquitinases (DUBs) . Subquinocin enhances the activation of NF-κB and IFN pathways by inhibiting CYLD. Subquinocin promotes RIG-I-mediated activation of IRF3 and/or IRF7 in the interferon pathway[1].
Product Specifications
UNSPSC
12352005
Target
Deubiquitinase; IFNAR; NF-κB
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; NF-κB
Field of Research
Cancer
Purity
99.83
Smiles
O=C1N(CC(C)C)C=C(NC(NC(CCSC)C(OC)=O)=O)C2=C1C=CC=C2
Molecular Formula
C20H27N3O4S
Molecular Weight
405.51
References & Citations
[1]Yamanaka S, et al. Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling. Biochem Biophys Res Commun. 2020 Mar 26;524 (1) :1-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![RAD21 Mouse Monoclonal Antibody [Clone ID: OTI6C10]](https://cdn.genprice.uk/products/937/68dd18bb061270361e908ab6/imageurl/cf811222.webp)
CF811222 100 µg
RAD21 Mouse Monoclonal Antibody [Clone ID: OTI6C10]
Sign In for Pricing
View Details 
BNC402173-100 1x 100 µL
Catenin, beta (CTNNB1) (rCTNNB1/2173), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 