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E3 Ligase Ligand-linker Conjugate 186

E3 Ligase Ligand-linker Conjugate 186 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 186 can be used to synthesize PROTAC SJ10542 (HY-145696) [1].

Product Specifications

CAS Number

[2789680-19-7]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Inflammation/Immunology

Smiles

NCCCN(CC1)CCN1C2=CC=C(C=C2)C3C(NC(CC3)=O)=O

Molecular Formula

C18H26N4O2

Molecular Weight

330.42

References & Citations

[1]Alcock LJ, et al. Development of Potent and Selective Janus Kinase 2/3 Directing PG-PROTACs. ACS Med Chem Lett. 2022 Feb 21;13 (3) :475-482.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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