(S, R, S) -AHPC-Amide-PEG2-C2-NH2
(S, R, S) -AHPC-Amide-PEG2-C2-NH2 is an E3 Ligase Ligand-Linker Conjugates that can be used to synthesize PROTAC PI3K/110β degrader-1.
Product Specifications
CAS Number
2138439-54-8
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(NCC1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@@H](NC(CCOCCOCCN)=O)C(C)(C)C)=O
Molecular Formula
C29H43N5O6S
Molecular Weight
589.75
References & Citations
[1]Cen J, et al. Double Swords in One: Novel Selective PI3K/110β PROTAC Degraders for the Treatment of Multidrug-Resistant Cancer by Activating ERS and Inhibiting P-gp. J Med Chem. 2025 May 8;68 (9) :9446-9464.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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