BBOX-IN-1

BBOX-IN-1 (compound 58) is a potent BBOX inhibitor with an IC50 of 0.02 μM. BBOX-IN-1 can be used in the study of triple negative breast cancer (TNBC) [1].

Product Specifications

CAS Number

[3106496-37-8]

UNSPSC

12352005

Target

Mitochondrial Metabolism

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(N1OCC2=CSC=N2)C(C(NC(C)(C)C(O)=O)=O)=C(O)C3=C1C=CC=C3

Molecular Formula

C18H17N3O6S

Molecular Weight

403.41

References & Citations

[1]Corner TP, et al. Derivatives of the Clinically Used HIF Prolyl Hydroxylase Inhibitor Desidustat Are Efficient Inhibitors of Human γ-Butyrobetaine Hydroxylase. J Med Chem. 2025 May 8;68 (9) :9777-9798.