Antifungal agent 132
Antifungal agent 132 (compound 25) is a selective and potent antifungal agent. Antifungal agent 132 inhibits Cryptococcus neoformans May1 with a Ki of 180 pM[1].
Product Specifications
UNSPSC
12352211
Target
Fungal
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C([C@H](CC1=CC=CN=C1)NC(C[C@H](O)[C@H](CC2=CC=CC=C2)N3)=O)NCCCCCCCCCCCCCC3=O
Molecular Formula
C33H48N4O4
Molecular Weight
564.76
References & Citations
[1]Kryštůfek R, et al. On-Resin Assembly of Macrocyclic Inhibitors of Cryptococcus neoformans May1: A Pathway to Potent Antifungal Agents. J Med Chem. 2025 May 8;68 (9) :9623-9637.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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