IRAK1/4/pan-FLT3 Kinase-IN-2
IRAK1/4/pan-FLT3 Kinase-IN-2 (compound 27) is a potent IRAK1/4 and FLT3 dual inhibitor with IC50s of 10, 0.7, and [1].
Product Specifications
CAS Number
[2760329-44-8]
UNSPSC
12352005
Target
IRAK
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
CC(C)OC1=CC2=NC=C(C3=C(F)C=C(F)C(N[C@H]4CNCC[C@@H]4F)=N3)N2C=C1
Molecular Formula
C20H22F3N5O
Molecular Weight
405.42
References & Citations
[1]Hoyt SB, et al. IRAK1/4/pan-FLT3 Kinase Inhibitors with Reduced hERG Block as Treatments for Acute Myeloid Leukemia. ACS Med Chem Lett. 2025 Apr 29;16 (5) :887-895.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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