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σ1R-IN-1

σ1R-IN-1 ((R, R) -1a) is a potent σ-1R inhibitor with an IC50 of 110 nM. σ1R-IN-1 is promising for research of neuropsychiatric disorders[1].

Product Specifications

UNSPSC

12352005

Target

Sigma Receptor

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

[C@@H]1(CCN2)[C@H]2CCCCN1CC3=CC=CC=C3

Molecular Formula

C15H22N2

Molecular Weight

230.35

References & Citations

[1]Carrel A, et al. Exploring Simple Drug Scaffolds from the Generated Database Chemical Space Reveals a Chiral Bicyclic Azepane with Potent Neuropharmacology. J Med Chem. 2025 May 8;68 (9) :9176-9201.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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