σ1R-IN-1
σ1R-IN-1 ((R, R) -1a) is a potent σ-1R inhibitor with an IC50 of 110 nM. σ1R-IN-1 is promising for research of neuropsychiatric disorders[1].
Product Specifications
UNSPSC
12352005
Target
Sigma Receptor
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
[C@@H]1(CCN2)[C@H]2CCCCN1CC3=CC=CC=C3
Molecular Formula
C15H22N2
Molecular Weight
230.35
References & Citations
[1]Carrel A, et al. Exploring Simple Drug Scaffolds from the Generated Database Chemical Space Reveals a Chiral Bicyclic Azepane with Potent Neuropharmacology. J Med Chem. 2025 May 8;68 (9) :9176-9201.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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