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3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid

3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid is a target protein ligand-linker conjugate that incorporates a ligand for c-Met (HY-451241) and a PROTAC linker (HY-W442078), which recruits E3 ligases. 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961) [1].

Product Specifications

CAS Number

[2230826-10-3]

UNSPSC

12352005

Target

C-Met/HGFR; Target Protein Ligand-Linker Conjugates

Related Pathways

PROTAC; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

FC1=CC=C(C=C1)NC(C2(C(NC3=CC(F)=C(C=C3)OC4=CC=NC5=C4C=C(C(OCCCOCCCOCCC(O)=O)=C5)OC)=O)CC2)=O

Molecular Formula

C36H37F2N3O9

Molecular Weight

693.69

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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