NH2-PEG-phenol-PEG-COOtBu
NH2-PEG-phenol-PEG-COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC BRD4 Degrader-14 (HY-138637) [1].
Product Specifications
CAS Number
[2417370-72-8]
UNSPSC
12352005
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(COCCC1=CC(OCCN)=CC(O)=C1)OC(C)(C)C
Molecular Formula
C16H25NO5
Molecular Weight
311.37
References & Citations
[1]Dragovich PS, et al. Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy. J Med Chem. 2021 Mar 11;64 (5) :2576-2607.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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