AHPC-PEG6-CH2COOH
AHPC-PEG6-CH2COOH is an E3 ligase ligand-linker conjugate that incorporates a VHL ligand and 6-unit PEG linker (HY-122702) . AHPC-PEG6-CH2COOH can be used for synthesis of PROTAC CMP98 (HY-136257) [1].
Product Specifications
CAS Number
[2361117-11-3]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(O)COCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)=O
Molecular Formula
C36H54N4O12S
Molecular Weight
766.90
References & Citations
[1]Alessio CIULLI, et al. Small molecules. WO2018189554A1. 2018-10-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Curated Selection
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