AZD9496-O-C3-O-C3-O-C-acid
AZD9496-O-C3-O-C3-O-C-acid is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for ERα and a PROTAC linker, which recruits E3 ligases. AZD9496-O-C3-O-C3-O-C-acid can be used for synthesis of PROTAC AZ'6421 (HY-135312).
Product Specifications
CAS Number
2361117-48-6
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(C)(F)CN1[C@H](C2=C(C=C(C=C2F)OCCCOCCCOCC(O)=O)F)C3=C(C[C@H]1C)C4=CC=CC=C4N3
Molecular Formula
C30H37F3N2O5
Molecular Weight
562.62
References & Citations
[1]Bin Yang, et al. Compounds and their use in treating cancer. Patent WO2019123367A1. 2019-06-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470218-100 1x 100 µL
CD100 (Semaphorin-4D) (A8), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880806-500 1x 500 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680270-500 1x 500 µL
Fibronectin (HFN7.1), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402895-500 1x 500 µL
C-Myc Oncoprotein (MYC2895R), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC610874-100 1x 100 µL
PLAP (Placental Alkaline Phosphatase) (GM022), CF660R conjugate, 0.1mg/mL
Sign In for Pricing
View Details