AZD9496-O-C3-O-C3-O-C-acid
AZD9496-O-C3-O-C3-O-C-acid is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for ERα (HY-12870) and a PROTAC linker, which recruits E3 ligases. AZD9496-O-C3-O-C3-O-C-acid can be used for synthesis of PROTAC AZ'6421 (HY-135312) [1].
Product Specifications
CAS Number
[2361117-48-6]
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(C)(F)CN1[C@H](C2=C(C=C(C=C2F)OCCCOCCCOCC(O)=O)F)C3=C(C[C@H]1C)C4=CC=CC=C4N3
Molecular Formula
C30H37F3N2O5
Molecular Weight
562.62
References & Citations
[1]Bin Yang, et al. Compounds and their use in treating cancer. Patent WO2019123367A1. 2019-06-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα
Curated Selection
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