Thalidomide-C-amide-C5-amine
Thalidomide-C-amide-C5-amine is an E3 ligase ligand. Thalidomide-C-amide-C5-amine can be used for synthesis of PROTAC BET Degrader-10 (HY-112718) [1].
Product Specifications
CAS Number
[1957236-06-4]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Smiles
NCCCCCC(NCC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O
Molecular Formula
C20H24N4O5
Molecular Weight
400.43
References & Citations
[1]Bradner J, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO2017007612A1. 2017-01-12
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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