TBK1 ligand 2-C-O-C4-O-C3-O-C-amide
TBK1 ligand 2-C-O-C4-O-C3-O-C-amide is a conjugate of TBK1 ligand and linker, which can be used in the synthesis of PROTAC TBK1 degrader-2.
Product Specifications
CAS Number
2052306-12-2
UNSPSC
12352005
Target
IKK; Target Protein Ligand-Linker Conjugates
Related Pathways
NF-κB; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(COCCCOCCCCOCCCOC1=CC=C(NC2=NC=C(C(NCCCN(C)C(C3CCC3)=O)=N2)Br)C=C1)O
Molecular Formula
C31H46BrN5O7
Molecular Weight
680.63
References & Citations
[1]Crew AP, et al. Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1. J Med Chem. 2018 Jan 25;61 (2) :583-598.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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