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TBK1 ligand 2-C-O-C4-O-C3-O-C-amide

TBK1 ligand 2-C-O-C4-O-C3-O-C-amide is a conjugate of TBK1 ligand and linker, which can be used in the synthesis of PROTAC TBK1 degrader-2.

Product Specifications

CAS Number

2052306-12-2

UNSPSC

12352005

Target

IKK; Target Protein Ligand-Linker Conjugates

Related Pathways

NF-κB; PROTAC

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(COCCCOCCCCOCCCOC1=CC=C(NC2=NC=C(C(NCCCN(C)C(C3CCC3)=O)=N2)Br)C=C1)O

Molecular Formula

C31H46BrN5O7

Molecular Weight

680.63

References & Citations

[1]Crew AP, et al. Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1. J Med Chem. 2018 Jan 25;61 (2) :583-598.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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