TBK1 ligand 2
TBK1 ligand 2 (Compound 1b) is a TBK1 inhibitor. TBK1 ligand 2 can be used for synthesis of PROTAC TBK1 degrader-2 (HY-112557) [1].
Product Specifications
CAS Number
[2052306-16-6]
UNSPSC
12352005
Target
IKK; Ligands for Target Protein for PROTAC
Related Pathways
NF-κB; PROTAC
Field of Research
Cancer
Smiles
O=C(C1CCC1)N(CCCNC2=NC(NC3=CC=C(C=C3)OCC)=NC=C2Br)C
Molecular Formula
C21H28BrN5O2
Molecular Weight
462.38
References & Citations
[1]Crew AP, et al. Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1. J Med Chem. 2018 Jan 25;61 (2) :583-598.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TBK1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1455212-01 0.5 mg (E-Coli)
Recombinant Human LysM and putative peptidoglycan-binding domain-containing protein 4 (LYSMD4), partial
Ask
View Details 
MBS1455212-02 0.05 mg (Baculovirus)
Recombinant Human LysM and putative peptidoglycan-binding domain-containing protein 4 (LYSMD4), partial
Ask
View Details MBS1455212-03 0.5 mg (Yeast)
Recombinant Human LysM and putative peptidoglycan-binding domain-containing protein 4 (LYSMD4), partial
Ask
View Details 
MBS1455212-04 0.05 mg (Mammalian-Cell)
Recombinant Human LysM and putative peptidoglycan-binding domain-containing protein 4 (LYSMD4), partial
Ask
View Details MBS1455212-05 1 mg (E-Coli)
Recombinant Human LysM and putative peptidoglycan-binding domain-containing protein 4 (LYSMD4), partial
Ask
View Details MBS1455212-06 0.1 mg (Baculovirus)
Recombinant Human LysM and putative peptidoglycan-binding domain-containing protein 4 (LYSMD4), partial
Ask
View Details