Dapansutrile (Standard)

Dapansutrile (Standard) is the analytical standard of Dapansutrile. This product is intended for research and analytical applications. Dapansutrile is a potent, orally active and selective NLRP3 inflammasome inhibitor. Dapansutrile has anti-inflammatory activity and decreases immune factor levels. Dapansutrile can be used for research of inflammatory diseases[1][2].

Product Specifications

CAS Number

[54863-37-5]

UNSPSC

12352100

Target

NOD-like Receptor (NLR) ; Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology; Cancer

Smiles

N#CCCS(=O)(C)=O

Molecular Formula

C4H7NO2S

Molecular Weight

133.17

References & Citations

[1]Sánchez-Fernández A, et, al. OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis. Front Immunol. 2019 Nov 1;10:2578.|[2]Toldo S, et, al. The NLRP3 Inflammasome Inhibitor, OLT1177 (Dapansutrile), Reduces Infarct Size and Preserves Contractile Function After Ischemia Reperfusion Injury in the Mouse. J Cardiovasc Pharmacol. 2019 Apr;73 (4) :215-222.