DDS5
DDS5 is a CD28 inhibitor with a kd of 175.57 µM. DDS5 significantly inhibits CD28-CD80 interaction (IC50: 332 µM) . DDS5 can be used for research of immune-mediated diseases, including inflammatory bowel disease and rheumatoid arthritis[1].
Product Specifications
CAS Number
[2871481-31-9]
UNSPSC
12352005
Target
CD28
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
COC1(C2)CCC2(C3=CN(CC4C(C)(C)CCO4)N=N3)CC1
Molecular Formula
C17H27N3O2
Molecular Weight
305.42
References & Citations
[1]Calvo-Barreiro L, et al. Surface Plasmon Resonance (SPR) -Based Workflow for High-Throughput Discovery of CD28-Targeted Small Molecules[J]. bioRxiv, 2025: 2025.06. 12.659248.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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