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TH10184-octanedioic acid

TH10184-octanedioic acid is a conjugate of the NUDT5 ligand (HY-176262) and the linker (HY-W001958) . TH10184-octanedioic acid can be used for synthesizing PROTAC NUDT5 degrader DDD2 (HY-176261) [1].

Product Specifications

UNSPSC

12352005

Target

Target Protein Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

COC(C=C1C(O2)=NN=C2CN3C(C(N(C(N4C)=O)C)=O)=C4N=C3N5CCN(C(CCCCCCC(O)=O)=O)CC5)=C(C=C1)C

Molecular Formula

C30H38N8O7

Molecular Weight

622.67

References & Citations

[1]Seher Alam, et al. A cell-based degrader assessment platform facilitates discovery of functional NUDT5 PROTACs. bioRxiv. June 19, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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