TH10184-octanedioic acid
TH10184-octanedioic acid is a conjugate of the NUDT5 ligand (HY-176262) and the linker (HY-W001958) . TH10184-octanedioic acid can be used for synthesizing PROTAC NUDT5 degrader DDD2 (HY-176261) [1].
Product Specifications
UNSPSC
12352005
Target
Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
COC(C=C1C(O2)=NN=C2CN3C(C(N(C(N4C)=O)C)=O)=C4N=C3N5CCN(C(CCCCCCC(O)=O)=O)CC5)=C(C=C1)C
Molecular Formula
C30H38N8O7
Molecular Weight
622.67
References & Citations
[1]Seher Alam, et al. A cell-based degrader assessment platform facilitates discovery of functional NUDT5 PROTACs. bioRxiv. June 19, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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