F3-PEG8-RiboTAC
F3-PEG8-RiboTAC is a RiboTAC that can specifically degrade the mRNA of the oncogene LGALS1. F3-PEG8-RiboTAC can induce tumor cell apoptosis and inhibit invasion. F3-PEG8-RiboTAC has anti-tumor activity and can be used in the research of tumors such as leukemia and triple-negative breast cancer. (RNase L ligand (HY-177030) ; RNA binder (HY-177031) ; Linker (HY-W019798) ) [1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Galectin; PROTACs
Related Pathways
Apoptosis; Immunology/Inflammation; PROTAC
Field of Research
Cancer
Smiles
O=C(N(CCNC(C1=CC=C(C)C(F)=C1)=O)CC2=CC=NC=C2)CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(NC3=C(C4=CC(C5=CC=C(CN(C)[C@@H](C6=CC=CC=C6)C(NC)=O)C=C5)=CC=C4)SC=C3)=O)=O
Molecular Formula
C66H84FN7O13S
Molecular Weight
1234.48
References & Citations
[1]Meyer SM, et al. Linker Optimization Enhances the Potency of Ribonuclease-Targeting Chimeras in Cancer Models. J Med Chem. 2025 Jun 26;68 (12) :12881-12903.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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