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DHFS-IN-1

DHFS-IN-1 (Compound 3) is a dihydrofolate synthetase (DHFS) inhibitor with an IC50 value of 2.6 μM. DHFS-IN-1 can be used in research on infectious diseases related to bacterial folate synthesis[1].

Product Specifications

CAS Number

[2995300-60-0]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

NC1=NC(N)=NC2=NC=C(CNC3=CC=C(C4(O)C(NC4)=O)C=C3)N=C12

Molecular Formula

C16H16N8O2

Molecular Weight

352.35

References & Citations

[1]Virgin-Downey B, et al. 3-Hydroxy-Beta-Lactam Inhibitors of Dihydrofolate Synthetase[J]. ACS Bio & Med Chem Au, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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