DHFS-IN-1
DHFS-IN-1 (Compound 3) is a dihydrofolate synthetase (DHFS) inhibitor with an IC50 value of 2.6 μM. DHFS-IN-1 can be used in research on infectious diseases related to bacterial folate synthesis[1].
Product Specifications
CAS Number
[2995300-60-0]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
NC1=NC(N)=NC2=NC=C(CNC3=CC=C(C4(O)C(NC4)=O)C=C3)N=C12
Molecular Formula
C16H16N8O2
Molecular Weight
352.35
References & Citations
[1]Virgin-Downey B, et al. 3-Hydroxy-Beta-Lactam Inhibitors of Dihydrofolate Synthetase[J]. ACS Bio & Med Chem Au, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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