Antitubercular agent-52
Antitubercular agent-52 (Compound 7k) is an antitubercular agent targeting Mycobacterium tuberculosis (Mtb) . Antitubercular agent-52 selectively inhibits the cytochrome bcc (cyt-bcc) electron transport chain of Mtb and also acts on cytochrome bd (cyt-bd) . Antitubercular agent-52 blocks electron transfer and ATP production by interfering with the key energy metabolism pathway of Mtb. Antitubercular agent-52 is promising for research of tuberculosis[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C1C2=C(CN(CC3=CC=C(C/N=C/C4=CC=C([N+]([O-])=O)O4)C=C3)C2)NC5=CC=CC=C51
Molecular Formula
C24H20N4O4
Molecular Weight
428.44
References & Citations
[1]Clariano M, et al. Pyrroloquinolone-Based Compounds as a Novel Antimycobacterial Chemotype. ACS Med Chem Lett. 2025 Jun 3;16 (6) :1139-1146.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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