15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivate of 15-Deoxy-Δ-12,14-prostaglandin J2 (HY-108568) . 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM[1][2][3].
Product Specifications
CAS Number
[1947405-90-4]
UNSPSC
12352211
Target
Drug Derivative; Endogenous Metabolite; PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Smiles
CCCCC/C=C/C=C1[C@H](C=CC\1=O)C/C=C\CCCC(OC(CO)CO)=O
Molecular Formula
C23H34O5
Molecular Weight
390.51
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PPARγ; PPARδ
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