FBnG-amino-PEG3-C2-azido

FBnG-amino-PEG3-C2-azido is a tag-linker conjugate that incorporates a degradation tag FBnG (HY-W073762) and a glycol linker (Amino-PEG3-C2-Azido) (HY-W021401) . FBnG-amino-PEG3-C2-azido can be used for synthesis of GPX4-AUTAC (HY-176220) [1].

Product Specifications

CAS Number

[3085085-29-3]

UNSPSC

12352005

Target

AUTACs; Autophagy

Related Pathways

Autophagy; PROTAC

Field of Research

Cancer

Smiles

[N-]=[N+]=NCCOCCOCCOCCNC([C@@H](NC(C)=O)CSC1=NC(C(N=C(N2)N)=O)=C2N1CC3=CC=C(C=C3)F)=O

Molecular Formula

C25H33FN10O6S

Molecular Weight

620.66

References & Citations

[1]Gong R, et al. GPX4-AUTAC induces ferroptosis in breast cancer by promoting the selective autophagic degradation of GPX4 mediated by TRAF6-p62. Cell Death Differ. 2025 May 20.