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CX116

CX116 is an orally active anti-inflammatory agent. CX116 exerts its effects by inhibiting the inflammatory response, reducing oxidative stress, protecting mitochondrial function, and counteracting apoptosis. CX116 bears acceptable toxicity, and can significantly protect renal tissue from Cisplatin (HY-17394) -induced damage. CX116 can be used for the study of Cisplatin-induced acute kidney injury (cis-AKI) [1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis

Related Pathways

Apoptosis

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Smiles

NC1=NC=C(C=C1C(NC2=CC=C(C=C2)NC(C)=O)=O)C3=CC=C(N=C3)N4CCOCC4

Molecular Formula

C23H24N6O3

Molecular Weight

432.48

References & Citations

[1]Lou Y, et al. Discovery of Novel Potent Molecule for Treating Cisplatin-Induced Acute Kidney Injury Driven by Phenotypic Screening. J Med Chem. 2025 Jun 12;68 (11) :12100-12124.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-176238/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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