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Lipophagy inducer 1

Lipophagy inducer 1 (Compound 2726.007) is a lipophagy inducer. Lipophagy inducer 1 has the primary activity of reducing lipid droplet accumulation and rescuing podocyte cell death. Lipophagy inducer 1 exerts its effects by activating lipophagy and regulating the LXR signaling pathway. Lipophagy inducer 1 can be used in the study of the treatment of diabetic nephropathy (DKD) and other diseases related to lipid metabolism disorders[1].

Product Specifications

UNSPSC

12352005

Target

Autophagy; LXR

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease

Smiles

O=C1N(CC)[C@H]([C@H](C)CC)CN1CCCC[C@H]2CN=C(CCCC3CCCCC3)N2

Molecular Formula

C25H46N4O

Molecular Weight

418.66

References & Citations

[1]Njeim R, et al. Novel Lipophagy Inducers as Potential Therapeutics for Lipid Metabolism Disorders. ACS Chem Biol. 2025 Jun 20;20 (6) :1406-1416.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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