PRMT5-IN-51
PRMT5-IN-51 (compound 16–19F) is a potent PRMT5 inhibitor. PRMT5-IN-51 shows antiproliferative activity[1].
Product Specifications
CAS Number
[3064668-92-1]
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(N1CC2=CC=C(C(N)=NC(N)=N3)C3=C2)CCC4=C1C(Cl)=CC=C4
Molecular Formula
C18H16ClN5O
Molecular Weight
353.81
References & Citations
[1]Shen Z, et al. Discovery and Mechanism of 16-19F, a Novel Synthetic Lethal Inhibitor of the PRMT5•MTA Complex in MTAP-Deleted Cancer Cells. ACS Chem Biol. 2025 Jun 20;20 (6) :1333-1346.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-176231/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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