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TTTE

TTTE is a sulfone bischalcone derivative. TTTE has major anti-necrotic, anti-inflammatory and anti-fibrotic activities. TTTE exerts regulatory effects by downregulating key molecules such as Caspase-3, TNF-α, NF-κB and TGF-β. TTTE can be used in the study of liver injury[1].

Product Specifications

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Field of Research

Inflammation/Immunology

Smiles

O=S(C1=CC=C(N2C(C)=C(N=N2)/C(C)=N/N=C3SC(C(C)=O)=NN\3C4=CC=CC=C4)C=C1)(C5=CC=C(N6N=NC(/C(C)=N/N=C7N(N=C(S\7)C(C)=O)C8=CC=CC=C8)=C6C)C=C5)=O

Molecular Formula

C42H36N14O4S3

Molecular Weight

897.02

References & Citations

[1]Rashdan HRM, et al. Towards novel liver injury therapies based on design, synthesis and therapeutic efficacy of novel sulfone bis-compound on liver necrosis. Sci Rep. 2025 May 20;15 (1) :17546.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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