TTTE
TTTE is a sulfone bischalcone derivative. TTTE has major anti-necrotic, anti-inflammatory and anti-fibrotic activities. TTTE exerts regulatory effects by downregulating key molecules such as Caspase-3, TNF-α, NF-κB and TGF-β. TTTE can be used in the study of liver injury[1].
Product Specifications
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
O=S(C1=CC=C(N2C(C)=C(N=N2)/C(C)=N/N=C3SC(C(C)=O)=NN\3C4=CC=CC=C4)C=C1)(C5=CC=C(N6N=NC(/C(C)=N/N=C7N(N=C(S\7)C(C)=O)C8=CC=CC=C8)=C6C)C=C5)=O
Molecular Formula
C42H36N14O4S3
Molecular Weight
897.02
References & Citations
[1]Rashdan HRM, et al. Towards novel liver injury therapies based on design, synthesis and therapeutic efficacy of novel sulfone bis-compound on liver necrosis. Sci Rep. 2025 May 20;15 (1) :17546.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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