SARS-CoV-2 Mpro-IN-45
SARS-CoV-2 Mpro-IN-45 (compound 28f) is an orally active Mpro inhibitor with IC50 values of 0.12 and 0.16 μM for HCoV-OC43 Mpro and SARS-CoV-2 Mpro, respectively. SARS-CoV-2 Mpro-IN-45 exhibits antiviral activity[1].
Product Specifications
CAS Number
[2992608-40-7]
UNSPSC
12352005
Target
SARS-CoV; Virus Protease
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C([C@H]1N(C(C2=CC3=C(N2)C=CC=C3)=O)[C@@]4([H])CCCC[C@]4(C1)[H])N[C@H](C=O)C[C@@H]5CCNC5=O
Molecular Formula
C25H30N4O4
Molecular Weight
450.53
References & Citations
[1]Hu S, et al. Development of Orally Bioavailable Octahydroindole-Based Peptidomimetic Derivative as a Broad-Spectrum Inhibitor against HCoV-OC43 and SARS-CoV-2. J Med Chem. 2025 Jun 12;68 (11) :10823-10844.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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