APOL1-IN-3

APOL1-IN-3 (Compound 1) is an APOL1 inhibitor. APOL1-IN-3 can be used in the research of kidney diseases[1].

Product Specifications

CAS Number

[2762826-72-0]

UNSPSC

12352005

Target

Apolipoprotein

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

FC(F)(C1=CC([C@@H](CO[C@@]23C[C@@H](C4=CN(C)N=N4)N[C@@H](C)C3)O)=C2S1)F

Molecular Formula

C16H19F3N4O2S

Molecular Weight

388.41

References & Citations

[1]Peter Jamison Rose. Process for preparing (2s,4s,4's,6s) -2-methyl-6- (1-methyl-1h-1,2,3-triazol-4-yl) -2', - (trieluoromethyl) -4',5'-dihydrospiro[piperidine-4,7'-thieno [2,3-c] pyran] -4'-ol. WO2025059054A1. Vertex Pharmaceuticals Incorporated. 2024-09-10.