Aurora kinase-IN-7

Aurora kinase-IN-7 (compound 4b) is an orally active and selective AURKB inhibitor. Aurora kinase-IN-7 can be used in the study of aggressive cancers[1].

Product Specifications

UNSPSC

12352005

Target

Aurora Kinase

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

CN1C=C(C=N1)C2=CC=C3C(N=CN=C3NC4=CC=C(C=C4)CC(NC5=CC(F)=CC=C5)=O)=C2

Molecular Formula

C26H21FN6O

Molecular Weight

452.48

References & Citations

[1]N- (3-fluorophenyl) -2- (4- ((7- (1-methyl-1H-pyrazol-4-yl) quinazolin-4-yl) amino) phenyl) acetamide as the first orally active selective aurora kinase B inhibitor. Eur J Med Chem. 2025 Sep 15;294:117735.