Aurora kinase-IN-7
Aurora kinase-IN-7 (compound 4b) is an orally active and selective AURKB inhibitor. Aurora kinase-IN-7 can be used in the study of aggressive cancers[1].
Product Specifications
UNSPSC
12352005
Target
Aurora Kinase
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
CN1C=C(C=N1)C2=CC=C3C(N=CN=C3NC4=CC=C(C=C4)CC(NC5=CC(F)=CC=C5)=O)=C2
Molecular Formula
C26H21FN6O
Molecular Weight
452.48
References & Citations
[1]N- (3-fluorophenyl) -2- (4- ((7- (1-methyl-1H-pyrazol-4-yl) quinazolin-4-yl) amino) phenyl) acetamide as the first orally active selective aurora kinase B inhibitor. Eur J Med Chem. 2025 Sep 15;294:117735.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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