PROTAC DDR1 degrader-1
PROTAC DDR1 degrader-1 is a PROTAC based DDR1 degrader (Red: DDR1 inhibitor , black: linker, Blue: E3 ligase ligand).
Product Specifications
CAS Number
3081612-73-6
UNSPSC
12352005
Target
Discoidin Domain Receptor; PROTACs
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
COC1=CC=C(C=C1C#CC2=CN=C(N=C2)NC3CCN(CC3)CCC(NC4=CC=C5C(N(CC5=C4)C6CCC(NC6=O)=O)=O)=O)C(NC7=CC(C(N)=O)=CC(C(F)(F)F)=C7)=O
Molecular Formula
C43H40F3N9O7
Molecular Weight
851.83
References & Citations
[1]Wang X, et al. Targeted degradation of DDR1 by proteolytic targeting chimera reverses immune exclusion for tumor immunotherapy. Eur J Med Chem. 2025 May 12;294:117750.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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