E3 Ligase Ligand-linker Conjugate 185
E3 Ligase Ligand-linker Conjugate 185 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 185 can be used to synthesize RP03707.
Product Specifications
CAS Number
3030500-92-3
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1NC(CCN1C2=NN(C)C3=C2C=C(F)C(C4CCN(C5CC6(CCNCC6)C5)CC4)=C3)=O
Molecular Formula
C25H33FN6O2
Molecular Weight
468.57
References & Citations
[1]Ji X, et al. Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC. J Med Chem. 2025 May 22;68 (10) :10238-10254.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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