HNF4 agonist 1
HNF4 agonist 1 (compound 46) is a potent HNF4 agonist. HNF4 agonist 1 activates HNF4α and HNF4γ with EC50s of 6 and 17 nM, respectively. HNF4 agonist 1 can be used in the study of maturity-onset diabetes of the young 1 (MODY-1) [1].
Product Specifications
UNSPSC
12352005
Target
Orphan Nuclear Receptor
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.37
Smiles
OC(C1=C(C=CC(C#CC2=C(C=C(C=C2)C)Cl)=C1)O)=O
Molecular Formula
C16H11ClO3
Molecular Weight
286.71
References & Citations
[1]Schallmayer E, et al. A First-in-Class Hepatocyte Nuclear Factor 4 Agonist. J Med Chem. 2025 May 8.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Amyloid beta (1-43 specific) Mouse Monoclonal Antibody [Clone ID: 6G12]](https://cdn.genprice.uk/products/937/68dd1899061270361e8fb771/imageurl/am00004pu-n.webp)
AM00004PU-N 100 µg
Amyloid beta (1-43 specific) Mouse Monoclonal Antibody [Clone ID: 6G12]
Sign In for Pricing
View Details 
![iFluor™ 488 Conjugated FOXO1A Recombinant Rabbit Monoclonal Antibody [SU33-01]](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea8262f/imageurl/ha720161f.webp)
HA720161F 100 µL
iFluor™ 488 Conjugated FOXO1A Recombinant Rabbit Monoclonal Antibody [SU33-01]
Sign In for Pricing
View Details 
BNC942243-500 1x 500 µL
Glutathione S-Transferase Mu3 (GSTM3) (CPTC-GSTMu3-1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 