ROCK-IN-12

ROCK-IN-12 (compound R3) is a selective ROCK inhibitor. ROCK-IN-12 can be used in the study of glaucoma[1].

Product Specifications

UNSPSC

12352005

Target

ROCK

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Inflammation/Immunology

Smiles

COC1=CC=CC(CN(CC2)CCC2C3=NNC(C4=CC=NC5=C4C=CN5)=C3)=C1

Molecular Formula

C23H25N5O

Molecular Weight

387.48

References & Citations

[1]Li Q, et al. Design, Synthesis, and Evaluation of Novel ROCK Inhibitors for Glaucoma Treatment: Insights into In Vitro and In Vivo Efficacy and Safety. J Med Chem. 2025 May 8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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