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JX10

JX10 is a senomorphic agent. JX10 suppresses the expression of p38 MAPK and NF-κB. JX10 exhibits competent antiaging effects in C. elegans, senescent cells, and aged mice[1].

Product Specifications

UNSPSC

12352005

Target

NF-κB; p38 MAPK

Related Pathways

MAPK/ERK Pathway; NF-κB

Field of Research

Metabolic Disease

Smiles

FC1=C(C=C(C2=C1)N(C(C3=CC=C(C=C3)OC)=CC2=O)C4CC4)N5CCN(CC5)CC

Molecular Formula

C25H28FN3O2

Molecular Weight

421.51

References & Citations

[1]Qiao S, et al. Discovery of Non-antibacterial Enrofloxacin Derivatives with Emerging Antiaging Effects through Drug Repurposing and Secondary Development. J Med Chem. 2025 May 9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

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