STING agonist-42
STING agonist-42 (compound 8a) is a potent STING agonist. STING agonist-42 activates STING in THP1 and RAW 264.7 cells with EC50s of 0.06 and 14.15 μM, respectively[1].
Product Specifications
CAS Number
2942231-48-1
UNSPSC
12352005
Target
STING
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Inflammation/Immunology
Smiles
FC1=CC(C(O[Li])=O)=C(NC(C2=NN=C(C=C2)N3C=NC(F)=C3)=O)C=C1C#C
Molecular Formula
C17H8F2LiN5O3
Molecular Weight
375.21
References & Citations
[1]Hou H, et al. Discovery of 3- (Fluoro-imidazolyl) pyridazine Derivatives as Potent STING Agonists with Antitumor Activity. J Med Chem. 2025 May 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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