E3 Ligase Ligand-linker Conjugate 184
E3 Ligase Ligand-linker Conjugate 184 is a E3 Ligase Ligand-Linker Conjugates, consisting of CDK2 ligand-2 (HY-176124) and the corresponding Linker. E3 Ligase Ligand-linker Conjugate 184 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete CDK2 degrader 2 (HY-163815) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1N(C)C2=C(C=CC=C2N1C3C(NC(CC3)=O)=O)N(CC4)CCC4CN5CCC(C(OC(C)(C)C)=O)CC5
Molecular Formula
C29H41N5O5
Molecular Weight
539.67
References & Citations
[1]Philip Collier, et al. Cdk2 degraders and uses thereof. WO2024039901A2. 2024-06-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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