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E3 Ligase Ligand-linker Conjugate 184

E3 Ligase Ligand-linker Conjugate 184 is a E3 Ligase Ligand-Linker Conjugates, consisting of CDK2 ligand-2 (HY-176124) and the corresponding Linker. E3 Ligase Ligand-linker Conjugate 184 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete CDK2 degrader 2 (HY-163815) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1N(C)C2=C(C=CC=C2N1C3C(NC(CC3)=O)=O)N(CC4)CCC4CN5CCC(C(OC(C)(C)C)=O)CC5

Molecular Formula

C29H41N5O5

Molecular Weight

539.67

References & Citations

[1]Philip Collier, et al. Cdk2 degraders and uses thereof. WO2024039901A2. 2024-06-27.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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